Pirates vs. Cubs Prediction Odds Picks

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2026-01-22 00:52:51 - Translate -

Pirates vs. Cubs Prediction Odds Picks - September

The and will take the field against the and on Tuesday at 7:40 p.m. ET in the second game of a three-game series at Wrigley Field. The favored Pirates have -122 moneyline odds to win against the underdog Cubs, who are listed at +103. Pittsburgh (-1.5) is favored on the run line. The total for the game has been set at 7.5 runs. Take a look at everything you need from a betting perspective on the...

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