1. Medication Layer

The GLP-1 medications (like semaglutide, tirzepatide though in micro-form) act to:

• Increase fullness (satiety) and reduce hunger

• Slow gastric emptying (so you feel full longer)

• Improve metabolic parameters (insulin sensitivity, etc)

By using a microdose rather than full dose, the intention is to reduce common side-effects (nausea, GI upset) while still tapping into the key mechanisms. Noom claims that around 70% of members in the microdose program report no side-effects at all.

2. Behavior & Habit Layer

Medication alone isn’t the full story. Noom emphasises behaviour change: daily lessons, tracking, coaching, logging of food and activity. Their data suggest those who use the coaching module achieve weight-loss faster and maintain better engagement.

3. Personalisation & Titration

Rather than a “one-size-fits-all” dose escalation, Noom claims to customise the microdose based on individual response, side-effect profile, BMI, weight-loss speed, etc. 

This “low-and-slow” model aims for a more tolerable path, especially for those who might fear side-effects or have been deterred from GLP-1 therapy before.

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