will take the mound for the in the second of a three-game series against the and on Saturday at 4:10 PM ET. The Orioles are the favorite in this one, at -155, while the underdog Astros have +131 odds to play spoiler. Baltimore is a 1.5-run favorite (at +104 odds). The over/under is 8.5 runs for the matchup (with -107 odds to hit the over and -113 odds to go under). Here's everything you need to know from a betting perspective on the Orioles-Astros game, regarding the run line, moneyline and total, plus expert picks. Astros vs. Athletics Highlights | MLB Orioles vs. Astros Game Information & Odds When: Saturday, June 22, 2024 at 4:10 PM ET Where: Minute Maid Park in Houston, Texas How to Watch on TV: MASN Favorite Favorite Moneyline Underdog Moneyline Total Over Total Odds Under Total Odds Run Line Favorite Run Line Odds Underdog Run Line Odds Orioles -155 +131 8.5 -107 -113 -1.5 +104 -124 Orioles vs. Astros Prediction Score Prediction: Orioles 4, Astros 3 Total Prediction: Under 8.5 runs Win Probabilities: Orioles 53%, Astros 47% Orioles vs. Astros Betting Insights The Orioles have entered the game as favorites 58 times this season and won 38, or 65.5%, of those games. This season Baltimore has won 18 of its 25 games, or 72%, when favored by at least -155 on the moneyline. The Orioles have a 60.8% chance to win this Kyle Korver Jersey game based on the implied probability of the moneyline. The Astros have been underdogs in 17 games this season and have come away with the win eight times (47.1%) in those contests. Houston has been listed as an underdog of +131 or more on two occasions this season and lost both games. Sportsbooks have implied with the moneyline set for this matchup that the Astros have a 43.3% chance of pulling out a win. Orioles Recent Betting Performance The Orioles were the moneyline favorite for six of their last 10 games, and went 3-3 in those matchups. In their last 10 matchups (all had set totals), the Orioles combined with their opponents to hit the over on the total five times. The Orioles' ATS record is 6-4-0 over their past 10 games. Orioles Recent Stats Stat Avg/Total Record 6-4 Runs Per Game 6.5 HR 19 ERA 4.15 K/9 8.2 Orioles Player Insights Henderson has gone yard 24 times in the 2024 campaign while knocking in 53 runs, both totals that lead the Orioles. Among all MLB hitters, Henderson ranks 23rd in batting average, 12th in on-base percentage, and third in slugging. Henderson carries a 14-game hitting streak into this matchup. In his last 10 games he is hitting .378 with five doubles, four home runs, four walks and eight RBI. has 53 runs batted in while hitting .305. Both are team-highs. Rutschman is 20th in home runs and 10th in RBI among all MLB hitters this season. Rutschman enters this matchup looking for his third game in a row with a hit. In his last five games he is batting .478 with two doubles, a home run, three walks and an RBI. is hitting .237 with 13 doubles, a triple, 20 home runs and 23 walks. Santander will look to build on his two-game hitting in this game. During his last five outings he is hitting .304 with three home runs, a walk and nine RBI. is hitting .278 with 15 doubles, five triples, 11 home runs and 16 walks. Westburg has recorded at least one hit in two straight games. During his last five outings he is batting .263 with a double, a home run and four RBI. Orioles Team Props Hits O/U Total Bases O/U HR O/U RBI O/U Jordan Westburg 0.5 (-255) 1.5 (+115) 0.5 (+500) 0.5 (+180) 0.5 (-275) 1.5 (+110) 0.5 (+425) 0.5 (+150) Anthony Santander 0.5 (-195) 1.5 (+110) 0.5 (+330) 0.5 (+140) Ryan O'Hearn 0.5 (-260) 1.5 (+105) 0.5 (+390) 0.5 (+150) Gunnar Henderson 0.5 (-280) 1.5 (-110) 0.5 (+295) 0.5 (+140) Astros Recent Betting Performance The Astros have played as underdogs in three of their past 10 games and have gone 2-1 in those contests. The Astros and their opponents have combined to hit the over three times in their last 10 games with a total. The Astros have six wins against the spread in their last 10 chances. Astros Recent Stats Stat Avg/Total Record 6-4 Runs Per Game 4.5 HR 6 ERA 3.98 K/9 9.1 Astros Player Insights Yordan Alvarez is batting .293 with 16 doubles, a triple, 15 home runs and 29 walks, while getting on base at a rate of .364. Alvarez's home run total puts him 17th in the majors, and he is 43rd in RBI. .301 batting average leads his team. Altuve is 45th in homers and 86th in RBI among all hitters in the big leagues. has 13 doubles, two triples, nine home runs and 24 walks while batting .250. is batting .274 with 10 doubles, a triple, five home runs and 12 walks. Astros Team Props Hits O/U Total Bases O/U HR O/U RBI O/U 0.5 (-270) 1.5 (+135) 0.5 (+950) 0.5 (+200) Jose Altuve 0.5 (-235) 1.5 (+135) 0.5 (+550) 0.5 (+205) 0.5 (-255) 1.5 (+115) 0.5 (+500) 0.5 (+160) Alex Bregman 0.5 (-235) 1.5 (+140) 0.5 (+600) 0.5 (+210) 0.5 (-115) 0.5 (-115) 0.5 (+850) 0.5 (+280) Baltimore Orioles' Adley Rutschman & New York Yankees' Aaron Judge headline Ben's Team of the Week Dylan Windler Jersey