Desiccated Thyroid vs Synthetic Thyroid Medications: Key Differences to Know
If you're looking to treat the symptoms of hypothyroidism among patients, medical specialists must take an informed choice among two primary types of treatments for thyroid diseases. Desiccated thyroid comes from the thyroid glands of animals. It's been in use since the beginning of time and modern solutions have ruled the market for many years. Understanding the fundamental differences between the two treatments can help patients make an informed choice to consult their medical professionals on which treatment is ideal for their needs.
What is Desiccated Thyroid?
Desiccated Thyroid is an organic thyroid hormone replacement made of dried and powdered the pork (pig) thyroid glands. It has all of the hormones healthy thyroid glands produce including those hormones T4 (thyroxine) together with T3 (triiodothyronine) and as lesser amounts in T1, T2 and the hormone called calcitonin. Brands such as Armour Thyroid Nature-Throid and Armour Thyroid and NP Thyroid have been utilized over time, and there are certain formulations dating into the second half of the 1800s. The reason for people to choose desiccated thyroid is due to its natural sources and also its nature to offer many thyroid hormones rather than just one chemical substance.
Understanding Synthetic Thyroid Medications
Synthetic thyroid drugs, in contrast, originate from labs and are created to mimic the effects of certain thyroid hormones. In most cases, the synthetic option is known as levothyroxine (found in the brand names Synthroid, Levoxyl, and Tirosint) it is the only brand with T4. It is believed that the body can convert the T4 into a T3 active hormone if it is needed. Patients with certain conditions may receive synthesized T3 (liothyronine) in the form of an individual or using T4 together. Synthetic medicines offer standard doses and are made in accordance with strict guidelines prescribed in the field of pharmaceuticals. This is why they are a popular choice for numerous endocrinologists.
Hormone Composition: A Critical Distinction
The main difference between these two types is their compositions of hormones. Desiccated thyroid contains an undetermined percentage of about 4:1 T4:3 which corresponds to the production by the thyroid gland in pigs. It's just not the same as the production of human thyroid. The human thyroid typically produce a percentage close to 14:1. That means that decomposed thyroid produces higher levels of T3 than the natural human thyroid produces.
Synthetic levothyroxine can be described as a drug only for T4 that is based on the body's conversion into the hormone T3. If the body's ability to transform T4 into T3, then this technique works. Some individuals could be affected by an impaired conversion due to the particular genetics that cause their disease as well as nutritional deficiencies and others, and can profit from the T3 source that's present in the an underhydrated thyroid.
Consistency and Standardization
Synthetic thyroid medicine provides the highest level of stability in dose to dose in addition to batch batches. The manufacturing process for pharmaceutical manufacturing assures that every tablet is containing what is listed in the product's labels. This makes doctors much more able change dosages so that they maintain the level of thyroid hormone that is steady for their patients.
Desiccated thyroid in accordance with FDA regulations and standards could have slight variation in the effectiveness of the batches due to the natural source. Manufacturers need ensure that every batch is in compliance with specific guidelines for thyroid hormones. But some people have experienced fluctuations when they shift between different brand names and many desiccated Thyroid medications.
Individual Response and Symptom Relief
The reactions of patients to these medications will differ dramatically. Many people respond well to levothyroxine synthesized in a lab, which is why they get regular lab outcomes and complete relief from the symptoms. Some suffer of persistent symptoms like extreme weight gain, headaches caused by fatigue and intolerant of cold even though their thyroid levels remain within the norm of synthetic substances.
Patients might experience greater results after making the switch to desiccated T3 or including T3 into the treatment with levothyroxine. The extra T3 that is found in desiccated thyroid may be helpful for those who struggle in converting from T4 to. But, the higher T3 levels could create problems for some people and may cause signs of hyperthyroidism like sleepiness, hypercardia and anxiety in the event that being taken into consideration.
Cost and Availability Considerations
Levothyroxine that is synthesized from synthetic sources can be cheaper than the desiccated thyroid medications, there are generic versions accessible for purchase at lower costs. It is readily available at all pharmacies and is usually is accepted by insurance plans which have very minimal copayments. Desiccated thyroid tends to be more expensive and may face problems with supply. Coverage for insurance differs, with certain insurance plans capable of covering it, as well as others that require prior approval use, or with higher cost copays.
Medical Community Perspectives
A majority of doctors favor synthetic levothyroxine to be the primary treatment of patients with thyroid hypothyroidism. Medical organizations important including the American Thyroid Association, recommend synthetic T4 as the ideal therapy due to its consistency, purity and predictability in drug's pharmacokinetics. Numerous endocrinologists are concerned by the inconsistentity of the T4-to-T3 ratios in desiccated medications and the difficulties when it comes to altering dosages.
Yet, a growing number of physicians are becoming aware that certain patients really benefit through desiccated or combined treatment. Integrative and functional medicine specialists typically recommend these treatments in cases where patients have problems that do not resolve despite frequent laboratory tests for medicines that are chemical.
Comprehensive Hormone Therapy: Optimizing Your Treatment
Find the most effective thyroid treatment is not the only aspect to an effective treatment of hormones for thyroid disorders. A comprehensive and effective treatment plan will look at each aspect of the hormonal system in the body and acknowledges the fact that the thyroid gland does not function in isolation. The cortisol levels as well as sex hormones, vitamin D among many other factors affect the efficacy of thyroid medication as well as the way you are feeling. Working with a physician that is familiar with the specifics of hormone therapy can aid you to improve not only the selection of thyroid medicines and treatments as well as to address your stress-related nutritional concerns, in addition to factors in your lifestyle that affect the functioning of your thyroid. If you choose to use synthesized or deiccated thyroid medicines, consulting qualified doctors who have an extensive approach to hormone therapy may help you distinguish between maintaining the laboratory results and feeling at your best.
Conclusion
The selection between desiccated and the synthetic thyroid medicine isn't a universal solution. Each has benefits and drawbacks. What is beneficial for one individual may not be appropriate for someone else. Synthetic levothyroxine offers consistency with regard to cost effectiveness, as well as broad acceptance in the medical community. In contrast desiccated thyroid is an effective multi-hormone therapy which some believe to be more effective. The decision to choose this option must be made in consultation with your doctor who takes into account your individual health conditions lab results, along with the medical history you have along with your expectations in terms of treatment. Regularly communicating and monitoring regarding how you're feeling with the medications you decide to use is essential, and changes may need to be implemented over time to maintain an optimal thyroid health and general well-being.
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